Don’t be hampered by the original problem statement. Believe that this problem can be solved and that you will enjoy working it out. Keep starting from first principles, explaining again and again what you are trying to do. As soon as a problem is stated, start right away to solve it. Moreover, asking questions forces them into the laborious task of thinking, which is why they fail to ask questions.” Savage’s approach to research, via Mosteller （copy from Jon McAuliffe’s webpage): Many people don’t want to ask questions because it exposes them to confront the reality of their circumstance, which may scare them.
A complete NGS workflow to generate a consensus sequence and haplotypes is discussed. Deep sequencing is highly important due to its ability to address an increasingly diverse range of biological problems such as the ones encountered in therapeutics. When you need to know the facts, you must inquire, not just make assumptions. Sequence analysis is incomplete without discussing next-generation sequencing (NGS) data. To become a great researcher, don’t answer your questions, but question your answers. The fact is that many people don’t ask any questions as they habitually guess their way by creating answers for themselves. Biological sequences generally refer to sequences of nucleotides or amino acids. Truly, you want to ask questions to gain clarity about the direction you are heading. Their assumptions actually hold them back from knowing the truth. “Most people assume that they know answers. Notably, the problem set includes all of the problems offered in Biological Sequence Analysis (BSA), by Durbin et al., widely adopted as a required text for. O Judge a man by his questions rather than his answers.īelow is quoted from Daniel Ally (I changed one word) in his contribution to Entrepreneur, also available in Insider: O What we see is the solution to a computational problem, our brains compute the most likely causes for the photon absorptions within our eyes. O The true logic of this world is in the calculus of probabilities. Analyzing their structures and functions to obtain useful knowledge is an urgent and important problem to be solved. The biological sequences are often coded by strings, and a large amount of sequence data has been generated and facilitated by recent advances in sequencing technology. Contact me: Department of Statistics, Harvard University, Cambridge, MA 02138. Biological macromolecules play a vital role in life activities. In many genome sequence projects, huge amount of sequence data is available in the successfully. Here is a profile article about me published by Harvard University Gazette in 2001. I am fascinated by biology and by nature wonders of all sorts. I love statistics, which is both my life and my fun I like bridge, soccer, badminton and skiing. Biological Sequence Embedding Based Classification for MERS and SARS. I am a teacher who wants to learn all the unknowns and a researcher who is fond of the beauty of mathematics and of the beings.
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